Radiesse is a world-known volumizing filler and stimulator designed to smooth moderate to severe facial wrinkles, while increasing the skin's own collagen and elastin production. The 2-in-1 filler has become one of the world's most used fillers to help restore lost volume and promotes a renewed skin structure over time. Radiesse comes in two formulations, with and without lidocaine, and is made of calcium hydroxylapatite (CaHA), which is stiffer and last longer than hyaluronic acid fillers (up to 15 months). This makes Radiesse ideal to use in areas such as the nasolabial folds, back of the hands, chin, and jawline.